A new breed of vampire are created using a unic chip that will give them the characteristics of a vampire. The Hellsing Organization, headed by Sir Integra Wingates Hellsing, handles in dealing with these vampires who threaten God and Her Majesty (Queen of England).

Alucard, a very powerful (maybe one of the orginal) vampires serves the huamns of the Hellsing Organization to rid the Earth of these "vampires". After a fateful meeting with police girl, Seras Victoria (who agrees to be transformed into a vampire to save her life) battles alongside her master Alucard and the Hellsing Organization.

"In the name of God, impure souls of the living dead shall be banished into eternal damnation. Amen"